患者,卓某,男,20岁,某大学金融系91级学生,1992年5月中因便秘,肛裂,自服牛黄解毒片(广州番禺市桥制药厂生产,批号不祥)4片,1小时后,患者手臂双侧出现皮疹,隔天皮疹自行消退。同年10月份又因便秘、肛裂再次自服牛黄解毒片4片,1小时后,同样又出现上述情况,患者手臂双侧又出现皮疹,若干个小时后,皮疹又自行消退。据有关文献资料记载,牛毒片所致过敏性休克,在国内有两例报遗;引起血小板减少有一例报道,而中药雄黄引起的砷角化病及砷黑变病则有4例报道,但牛黄解毒片中的其他成分如:冰片、牛黄、桔梗、大 Patients, Zhuo, male, 20 years old, a university 91 Department of Finance students, in May 1992 due to constipation, anal fissure, self serving Niuhuangjiedu tablets (Guangzhou Panyu Shiqiao Pharmaceutical Factory, batch number ominous) 4, 1 After hours, patients with rash on both sides of the arm, the other day the rash subsided. In October the same year because of constipation, anal fissure once again serve Niuhuangjiedu tablets 4, 1 hour later, the same situation again, patients with bilateral rash on both sides of the arm, a few hours later, the rash subsided on their own. According to the literature records, bovine drug-induced anaphylactic shock, there are two reported in the country; caused by thrombocytopenia in one case reported, while the Chinese medicine realgar caused by arsenic keratosis and arsenic melanosis are reported in 4 cases, However, other components of bezoar detoxification tablets such as: borneol, bezoar, Campanulaceae, large