神经内分泌肿瘤(neuroendocrine tumors,NETs)是一组起源于肽能神经元和神经内分泌细胞的异质性肿瘤,可发生于全身多脏器,包括胃肠道、胰腺、胆管和肺、肾上腺髓质、副神经节、甲状腺、甲状旁腺及其他部位的神经内分泌细胞,其中胃肠胰NETs最常见,占所有NETs的55%～70%[1]。流行病 Neuroendocrine tumors (NETs) are a group of heterogeneous tumors that originate from peptide neurons and neuroendocrine cells and can occur in whole body multiple organs including the gastrointestinal tract, pancreas, bile duct and lung, adrenal medulla , Ganglion, thyroid, parathyroid and other parts of the neuroendocrine cells, of which gastrointestinal pancreatic NETs the most common, accounting for 55% to 70% of all NETs [1]. Epidemic