报道了牙鲆养殖过程中发生的体表溃烂综合症的病理组织变化。该病的病原有盾纤类纤毛虫指状拟舟虫和致病菌兔莫拉氏菌。指状拟舟虫不仅寄生于牙鲆体表皮肤、鳍 ,亦可侵入腹腔、肾脏、肌肉、心脏甚至脑。兔莫拉氏菌大量寄生于心脏血液中 ,随血液循环至各组织器官 ,引起牙鲆肝脏、肾脏及脾脏组织病变。指状拟舟虫和兔莫拉氏菌共同导致牙鲆死亡。 The histopathological changes of surface ulceration syndrome occurred during the cultivation of Japanese flounder were reported. The pathogen of the disease is a shield fibroid ciliate finger-like canid and pathogenic bacteria Moraxella. Finger-like parasites not only parasitic in flounder surface skin, fins, but also invade the abdominal cavity, kidney, muscle, heart and brain. A large number of Moraxella parasites in the bloodstream of the heart, with the blood circulation to various tissues and organs, causing turbot liver, kidney and spleen tissue lesions. Finger-like canid and Moraxella together lead to the death of Japanese flounder.