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婴儿肝炎综合征37例,初诊为2～3月龄,同步检测谷丙转氨酶(ALT 旧称S-GPT)、谷草转氨酶(AST 旧称S-GOT)及γ-谷氨酰转肽酶(γ-GT)活性,其均值有明显升高,三者的2/3病例均值分布在41～200u 范围内。ALT 与AST,γ-GT 与AST 二对直线相关均呈正相关,直线回归平行变动(P<0.05～0.01).AST/ALT 比值<1.5者19例,>1.5者18例,γ-GT/STA 比值<1者25例,>1者12例。上述均提示婴肝初期不仅有肝细胞膜通透性增高,而且有肝细胞微粒体破坏的急性肝脏炎症或坏死性病变。如能三者同时检测对婴肝转归具有参考价值。
Thirty-seven cases of infant hepatitis syndrome were newly diagnosed at 2 to 3 months of age. Simultaneous detection of alanine aminotransferase (S-GPT), aspartate aminotransferase (AST) and γ-glutamyl transpeptidase ) Activity, the average value was significantly increased, the average of 2/3 of the three cases distributed in the range of 41 ~ 200u. There was a positive correlation between ALT and AST, the linear correlation between γ-GT and AST, and the linear regression had a parallel change (P <0.05-0.01), 19 patients with ALT / AST ratio <1.5, 18 patients> 1.5, The ratio of <1 in 25 cases,> 1 in 12 cases. The above all suggest that not only the early stage of infant liver cell membrane permeability increased, and liver cell microsomal destruction of acute liver inflammation or necrotic lesions. If the three simultaneous detection of infant liver metastasis has a reference value.