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目的 :探讨中青年食管癌患者的临床、内镜及病理特点。方法 :以病例对照的方法进行分析 49例中青年(≤ 5 0岁 )食管癌患者的特点 ,选用同期 5 0岁以上的食管癌患者 182例为对照组。结果 :中青年食管癌患者主要表现为胸骨后疼痛 ,肿瘤多位于上胸段食管。内镜下进展期癌以Ⅰ型为主 ;早期癌诊断率低 ,主要为食管粘膜有局灶性充血、糜烂、粗糙隆起或凹陷 ;病理分化程度低 ,恶性度高。结论 :中青年食管癌患者的症状不典型 ,早期诊断困难 ,预后差
Objectives: To explore the clinical, endoscopic and pathological features of middle-aged and young patients with esophageal cancer. METHODS: A case-control study was performed to analyze the characteristics of 49 young and middle-aged (≤50 years) patients with esophageal cancer. 182 patients with esophageal cancer over the age of 50 years were selected as the control group. RESULTS: The patients with esophageal cancer in the young and middle-aged mainly presented with poststernal pain. The tumors were mostly located in the upper thoracic esophagus. Endoscopic advanced cancer type I; early cancer diagnosis rate is low, mainly for esophageal mucosa with focal hyperemia, erosion, rough uplift or depression; pathological differentiation is low, high degree of malignancy. Conclusion: The symptoms of young and middle-aged patients with esophageal cancer are not typical. Early diagnosis is difficult and the prognosis is poor.