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嗅觉记忆与生命活动中的多种基本功能甚至高级功能有密切关系,如辨别气味、增进食欲、识别环境、报警等本能行为。从进化史看,嗅觉系统具有较高的保守性,属于神经系统中最古老的旧皮质~([1]),可以通过中枢神经系统影响人的学习记忆、情绪、睡眠及调节生命周期等。近年来,研究提示嗅觉中枢本身可参与学习记忆过程,同时与抑郁、焦虑状态有关~([2-4])。因此,嗅觉缺损模型对研究学习记忆机制、抑郁症、帕金森、阿尔茨海默病
Smell memory and life activities in a variety of basic functions and even advanced features are closely related, such as the identification of odor, increase appetite, identify the environment, alarm instinct behavior. From the perspective of evolution, the olfactory system is highly conserved and belongs to the oldest old cortex in the nervous system. It can affect people’s learning and memory, mood, sleep and regulatory life cycle through the central nervous system. In recent years, studies suggest that the olfactory center itself can participate in learning and memory process, at the same time with the depression and anxiety state ~ ([2-4]). Therefore, the model of olfactory dysfunction in the study of learning and memory mechanisms, depression, Parkinson’s disease, Alzheimer’s disease