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近交系615小鼠可移植性肝细胞性肝癌是一种自发性肿瘤。由我院病理生理教研室培育成株。现传至38代,已稳定建株。本实验的目的是观察615小鼠在接种该肿瘤细胞后,不同生长时间肿瘤的形态改变,瘤组织周围的嗜银纤维反应和炎细胞浸润情况。材料和方法 (一)动物:615系种鼠自简阳中国医学科学院血液学研究所引入,在我院肿瘤研究组动物室常规饲养繁殖。实验所用小鼠,鼠龄一般在2～3个月,体重20～24g,各组雌雄数均等,随机分组。
Inbred Line 615 Mouse Transplantable Hepatocellular carcinoma is a spontaneous tumor. Pathology and Physiology Department by our hospital to cultivate adult. It has been to 38 generations, has been stable construction. The purpose of this experiment was to observe the morphological changes of tumor at different growth stages, the argyrophilic fiber reaction and the infiltration of inflammatory cells in the 615 mice after inoculation with the tumor cells. Materials and Methods (I) Animals: 615 mice were introduced from Jianyang Institute of Hematology, Chinese Academy of Medical Sciences, and housed and reared routinely in the animal laboratory of the Cancer Research Group in our hospital. The mice used in the experiment were generally 2 to 3 months old and weighing 20 to 24g. The numbers of male and female in each group were equal and randomly divided into groups.