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雄激素剥夺疗法作为晚期前列腺癌的标准疗法迄今已有50余年。去势手术对多数患者起初有效,但最终会发展为去势抵抗性前列腺癌(CRPC),主要原因是前列腺癌的发生和发展与雄激素受体
Androgen deprivation therapy has been the standard treatment for advanced prostate cancer for more than 50 years. Ovariectomy is initially effective in most patients, but eventually develops into castrate-resistant prostate cancer (CRPC), mainly due to the occurrence and progression of prostate cancer associated with androgen receptor