论文部分内容阅读
目的:研究孕妇缺钙缺锌及CA125水平升高是否导致胎膜早破(PROM)。方法:选取2010年5月至2011年6月我院收治的150例PROM孕妇为观察组,对照组为同孕周150例无PROM的健康孕妇,观察组在诊断为胎膜早破后立即抽取外周血2mL,对照组于入院时采血,测定两组患者中血清钙锌及CA125水平。结果:PROM孕妇血清钙锌含量明显低于对照组(P<0.05)。PPOM组孕妇产前血清CA125水平明显高于对照组(P<0.05)。结论:PPOM患者血清钙锌含量明显降低,血清CA125水平明显增高,提示孕妇血清中钙锌及CA125水平与胎膜早破有关,可以指导临床孕妇规范补充钙锌制剂,检查CA125水平升高,应注意患者是否有炎症发生,及时干预炎症,防止PROM的发生。
Objective: To study if calcium deficiency and zinc deficiency in pregnant women and elevated CA125 lead to premature rupture of membranes (PROM). Methods: 150 pregnant women treated with PROM in our hospital from May 2010 to June 2011 were selected as the observation group. The control group consisted of 150 pregnant women without PROM at the same gestational age. The observation group was taken immediately after the diagnosis of premature rupture of membranes Peripheral blood 2mL, the control group on admission blood, serum Ca, Zn and CA125 levels were measured in two groups. Results: Serum calcium and zinc levels in PROM pregnant women were significantly lower than those in control group (P <0.05). Prenatal serum CA125 level in PPOM group was significantly higher than that in control group (P <0.05). Conclusion: Serum calcium and zinc levels in patients with PPOM were significantly lower, serum CA125 levels were significantly higher, suggesting that serum levels of calcium, zinc and CA125 in pregnant women are related to premature rupture of membranes and can guide clinical pregnant women to standardize calcium and zinc preparations. Pay attention to whether patients have inflammation, timely intervention of inflammation, prevent the occurrence of PROM.