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目的:研究幽门螺旋杆菌(Hp)感染的细菌密度与不同程度慢性胃炎的关系。方法:选择有上消化道症状患者行微量胶囊14C-尿素呼气试验检查,用气体同位素质谱仪检测同位素标记CO2的量;选择Hp阳性患者118例进行胃镜检查,镜下考虑胃炎者详细记录病史,采图做出胃镜诊断,同时送病理活检、改良Giemsa染色,按慢性炎症程度分度行相关性分析。结果:Hp感染的细菌量与不同程度慢性胃炎的关系有统计学意义(χ2=27.621,P=0.001)。Hp感染的细菌量与慢性胃炎的程度呈正相关(r=0.457 669,P=0.001)。结论:Hp感染的细菌密度与慢性胃炎有密切关系。
Objective: To study the relationship between the bacterial density of Helicobacter pylori (Hp) infection and chronic gastritis with different degrees. Methods: The patients with upper gastrointestinal symptoms were examined by micro-capsule 14C-urea breath test, the amount of isotope-labeled CO2 was detected by gas isotope mass spectrometry, gastroscopy was selected in 118 cases of Hp positive patients, , Gastroscopy to make a map to take the diagnosis, while biopsy sent to improve Giemsa staining, according to the degree of chronic inflammation degree line correlation analysis. Results: There was a significant relationship between the amount of bacteria infected by Hp and the degree of chronic gastritis (χ2 = 27.621, P = 0.001). The amount of bacteria infected with Hp was positively correlated with the degree of chronic gastritis (r = 0.457 669, P = 0.001). Conclusion: The bacterial density of Hp infection is closely related to chronic gastritis.