开展中药提取小分子与蛋白质之间的作用研究,可为实现中药现代化战略进程提供基础理论依据和指导。本文介绍了近年来中药活性成分与蛋白质相互作用相关研究的主要技术和方法(包括光谱法、平衡透析法、电化学法、色谱法、质谱法、核磁共振、共振散射、分子模拟等),综述了二者相互作用的部分研究成果,并对该领域的未来发展前景进行了展望。 To study the role of traditional Chinese medicine extraction of small molecules and proteins can provide the theoretical basis and guidance for the realization of the modernization strategy of traditional Chinese medicine. In this paper, the main techniques and methods (including spectrometry, equilibrium dialysis, electrochemistry, chromatography, mass spectrometry, nuclear magnetic resonance, resonance scattering, molecular simulation, etc.) related to the interaction between active ingredients and proteins in traditional Chinese medicine The part of the research results of the interaction between the two, and prospects for the future development of the field.