Angew.Chem.Int.Ed.2016,55,9168~9172吲哚和氮杂吲哚结构是多种天然产物和药物分子的核心结构,发展合成这类结构的高效、绿色合成方法学具有重要的意义.厦门大学固体表面物理化学国家重点实验室徐海超和吕鑫等利用电化学方法实现了分子内芳胺和炔烃的[3+2]环化反应.该环化反应既可用于合成高取代吲哚,也可得到合成上具有挑战性的复杂氮杂吲哚.该反应是 Angew.Chem.Int.Ed.2016,55,9168 ~ 9172 Indole and azaindole structures are the core structures of many natural products and drug molecules. It is important to develop efficient and green synthetic methodology for the synthesis of such structures The [3 + 2] cyclization reaction of aromatic amines and alkynes in the molecule was realized by electrochemical methods, such as Xu Haichao and Lu Xin, State Key Laboratory of Solid Surface Physical Chemistry, Xiamen University. This cyclization reaction can be used to synthesize highly substituted indole The synthetically challenging complex azaindole can also be obtained