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许多数据表明长期失重以后立位耐力降低可能与压力感受性反射功能的改变有关。本文比较了两组被试者15天低动力卧床前后的立位耐力。以血压调节模型为基础分析了两种不同方式卧床前后单纯立位和下身负压加立位时压力感受性反射功能的改变,并用颈部加压及下身负压对中枢调节功能改变进行了观察。结果表明严格的头低位卧床后,立位耐力下降及压力感受性反射功能改变明显大于半日平卧半日倚坐者。而压力感受性反射功能的改变,特别是中枢神经系统调节功能的紊乱,是卧床后立位耐力降低的主要原因。从这种考虑为基础,作者提出了改变失重或模拟失重状态下的血液分布,调整对压力感受器的刺激,可能是预防心血管失调的有效方法。
Numerous data suggest that reduction in standing stamina after long-term weight loss may be related to changes in baroreflex function. This article compared the two groups of subjects 15 days low bed rest before and after standing position. Based on the blood pressure regulation model, the changes of baroreflex function in two different ways of standing standstill and lower body negative pressure plus standing position before and after bed rest were analyzed, and the changes of central adjusting function were observed with neck pressure and lower body negative pressure. The results showed that the strict head low bed rest, standing stamina and baroreflex function changes significantly greater than half-day lying half-day sit on. The baroreceptor reflex function changes, especially the central nervous system dysfunction disorder, is the main reason for reduced standing stamina after bed rest. Based on this consideration, the authors propose that altering the blood distribution under weightlessness or simulated weightlessness and adjusting baroreceptor stimulation may be an effective way to prevent cardiovascular disorders.