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放射治疗在小细胞肺癌的治疗中,始终有重要的地位。然而,近几年来,在生物学、分期和化疗方面的研究取得很大的进展,致使它的作用投下阴影。这导致放疗在治疗方面是否还存在有任何价值的争论。作者将简要地归纳当前的治疗状况,尤其是以随机研究材料为根据,试图确定合理的应用放疗的方法并着重于未肯定的需要进一步研究的领域。局限性病变的放疗治疗反应局部区域放疗加单药或联合化疗能达到明显改善存活率已在5个研究中得到证实。在这些研究中,最大数量的研究即医学研究会第二次236例小细胞肺癌的研究,中数存活期(MST)从
Radiation therapy has always played an important role in the treatment of small cell lung cancer. However, in recent years, great progress has been made in research on biology, staging, and chemotherapy, which has cast a shadow on its role. This has led to debate on the value of radiotherapy in treatment. The author will briefly summarize the current treatment situation, especially based on randomized study materials, trying to determine a reasonable method of applying radiotherapy and focusing on unrecognized areas that require further study. Localized radiotherapy response to localized lesions Local radiotherapy combined with single or combination chemotherapy can achieve significant improvements in survival rates that have been demonstrated in five studies. In these studies, the largest number of studies, the Medical Research Association, conducted the second study of 236 patients with small cell lung cancer, with median survival (MST) from