热毒宁联合头孢哌酮舒巴坦钠对多重耐药菌呼吸道感染患儿临床疗效及安全性研究

来源 :中华中医药学刊 | 被引量 : 0次 | 上传用户:wuwenwu321
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
目的:探讨热毒宁联合头孢哌酮舒巴坦钠对多重耐药菌呼吸道感染患儿临床疗效及安全性。方法:选择65例多重耐药菌呼吸道感染患儿进行随机分组对照研究,对照组32例患儿予头孢哌酮舒巴坦静点治疗,治疗组33例患儿在此基础上予热毒宁注射液辅助治疗,3 d为1个疗程,两组患儿均治疗1个疗程。通过比较治疗前后两组患儿临床症状变化以及治疗后的总有效率和TESS评分来探究热毒宁联合头孢哌酮舒巴坦钠对多重耐药菌呼吸道感染患儿临床疗效及安全性。结果:治疗前,两组患儿发热症状评分比较差异无统计学意义(P>0.05);治疗后,两组患儿的发热症状评分均降低(P<0.05),其中治疗组评分比对照组低(P<0.05)。治疗前,两组患儿流涕症状评分比较差异无统计学意义(P>0.05);治疗后,两组患儿的流涕症状评分均降低(P<0.05),其中治疗组评分比对照组低(P<0.05)。治疗前,两组患儿咳嗽症状评分比较差异无统计学意义(P>0.05);治疗后,两组患儿的咳嗽症状评分均降低(P<0.05),其中治疗组评分比对照组低(P<0.05)。治疗3 d后,对照组治愈11例(34.38%),好转13例(40.63%),无效8例(25.00%),总有效率为75.00%;治疗组治愈18(56.25%)例好转14(42.42%)无效1(3.03%),总有效率为90.91%。治疗组的治疗有效率比对照组较高(P<0.05)。在治疗1 d时,对照组TESS评分为1.23±0.17,治疗组TESS评分为1.25±0.15,两组之间无明显差异(P>0.05);治疗3 d时对照组TESS评分为1.32±0.18,治疗组TESS评分为1.34±0.19,两组TESS评分无明显差异(P>0.05)。结论:热毒宁联合头孢哌酮舒巴坦钠对多重耐药菌呼吸道感染患儿的治疗有良好的临床疗效而且及安全性较好。 OBJECTIVE: To investigate the clinical efficacy and safety of combination thermodin and cefoperazone sulbactam sodium in children with multi-drug resistant respiratory tract infection. Methods: A total of 65 children with multiple drug-resistant bacterial respiratory tract infections were randomly divided into control group, 32 patients in the control group were treated with cefoperazone sulbactam intravenously, and 33 children in the treatment group were treated with heat-toxin Injection adjuvant therapy, 3 d for a course of treatment, two groups of children were treated with a course of treatment. The clinical efficacy and safety of Revitonine plus cefoperazone and sulbactam sodium in children with multi-drug resistant respiratory tract infection were explored by comparing the changes of clinical symptoms and the total effective rate and TESS score after treatment. Results: Before treatment, there was no significant difference in febrile symptom scores between the two groups (P> 0.05). After treatment, the fever symptom scores of both groups were decreased (P <0.05), and the score of the treatment group was higher than that of the control group Low (P <0.05). Before treatment, there was no significant difference in runny nose symptom scores between the two groups (P> 0.05). After treatment, the scores of runny nose symptoms in both groups were decreased (P <0.05), and the score of treatment group was higher than that of control group Low (P <0.05). Before treatment, there was no significant difference in cough symptom scores between the two groups (P> 0.05). After treatment, the cough symptom scores of both groups were decreased (P <0.05), and the score of the treatment group was lower than that of the control group P <0.05). After 3 days of treatment, the control group was cured in 11 cases (34.38%), improved in 13 cases (40.63%), ineffective in 8 cases (25.00%), the total effective rate was 75.00% 42.42%) invalid 1 (3.03%), the total effective rate was 90.91%. The therapeutic efficiency of the treatment group was higher than that of the control group (P <0.05). The TESS score was 1.23 ± 0.17 in the control group and 1.25 ± 0.15 in the treatment group at 1 d after treatment. There was no significant difference between the two groups (P> 0.05). The TESS score of the control group was 1.32 ± 0.18 at 3 d after treatment, TESS score of the treatment group was 1.34 ± 0.19, there was no significant difference between the two groups (P> 0.05). CONCLUSION: The combination of Rendoxin and cefoperazone sulbactam sodium has good clinical efficacy and safety for children with multi-drug resistant respiratory tract infection.
其他文献
本文以北京某地下室工程为例,研究了超长墙体的温度应力影响因素,提出了以预应力技术、增设温度筋来“抗”、以后浇带设置工艺来“放”、以减小约束,减小混凝土温度变形措施
文章通过对古代私家藏书的功与过方面的剖析,给出二则对文献管理者的人文启示。一是藏书家对书极为珍视,其原因为:嗜书成癖和5条聚书之苦;二是书得之不易,存之更不易,并列举
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
期刊
天然气液化对环境和安全将有一定影响,尤其是天然气液化厂“三废”的排放严重恶化了当地的生态和生存环境,造成巨大的经济损失。本文从环境保护的角度出发,分析了天然气液化
基本概念是基础知识结构和功能的基本单位,是人类思维活动的基本方式,也是思维活动的结果。总复习首要的任务是让学生理解和掌握基本概念,而对基本概念的理解,又有助于知识
近年来,我国的对二甲苯(下简称PX)需求量水涨船高,但是抵制PX工程项目上马的“邻避”运动也在各地此起彼伏。从厦门到大连,再到昆明、茂名,多年来,围绕PX项目污染环境的争议
CPD讯8月5日消息伊朗石油部长赞格内近日表示,伊朗将把向邻国输气作为优先重点。赞格内表示,目前,向欧洲输送天然气是不经济的,他们不会考虑天然气的价格问题。相反,他们将只
我国有260所高等师范,占全部高校1084所的四分之一;全国在校大学生200万,高师学生也占了四分之一,达50万人。现有的中等学校的师资,基本上靠高师培养。因此,高师当前遇到的
如何上好生理卫生复习课?我利用直观教具指导学生阅读,取得一定的效果,现以“泌尿系统”一节复习课为例。 1.利用直观教具使学生获得感性知识课前把学生带到实验室,凡涉及到
语文科是具有较强思想性的工具学科。 语文教师应该时刻注意把语文的工具教学和语文的思想教育结合起来。 一般情况下,在讲读教学中,语文教师是不会忘记利用选文本身思想内容