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作者报告1例39岁,女性患者,于1978年6月在左臀部出现一发展迅速的皮肤破溃。此前1974年、1976年该处发生过同样溃疡两次。发病前伴有多关节炎。从18岁开始患白癜风,并有枯草热和湿疹。体检:在左臀下外侧有一大而界限清楚的皮肤溃疡并延及左大腿后侧面,溃疡表面部分覆以血性渗出物,分离之则显露出血的皮下组织,溃疡边缘清楚、肿胀并呈蓝色。化验:血沉38mm/小时,类风湿因子阴性,抗核抗体1∶40阳性,甲状腺微粒体抗体1∶40阳性,无冷沉淀的免疫复合物,X 线检查有广泛的侵蚀性多关节炎。
The authors report a 39-year-old female patient who developed a rapidly developing skin ulceration on the left hip in June 1978. Earlier in 1974, 1976, the same ulcer occurred twice. Pre-onset with polyarthritis. From the age of 18 suffering from vitiligo, and hay fever and eczema. Physical examination: there is a large but well-defined skin ulcer outside the left buttocks and extends to the posterior aspect of the left thigh. The surface of the ulcer is covered with bloody exudate, and the subcutaneous tissue of the bleed is exposed. The ulcer has a clear edge and swollen with a blue color. Assay: erythrocyte sedimentation rate 38mm / h, rheumatoid factor negative, antinuclear antibody 1:40 positive, thyroid microsomal antibody 1:40 positive, no precipitation of immune complexes, X-ray examination has a wide range of aggressive polyarthritis.