目的探讨艾迪注射液改善晚期恶性肿瘤患者生活质量的疗效。方法采用随机双盲法将96例患者分为2组,治疗组在化疗基础上加用艾迪注射液,对照组单用化疗。完成1个以上疗程的患者进行疗效、卡氏评分、T细胞亚群、外周血象及肝肾功能、临床症状等变化的测定及观察,2组进行对比。结果近期疗效治疗组有效率44%,对照组43%,2组无明显差别;卡氏评分治疗组56%,对照组26%,2组差异有显著性(P<0.05);多数免疫功能指标及外周血象2组差异有显著性(P<0.05);临床症状改善2组差异有显著性(除恶心呕吐P<0.05外,余P<0.01)。结论艾迪注射液配合化疗治疗晚期恶性肿瘤具有调节免疫、减轻化疗毒副作用、改善患者生活质量的作用,是治疗晚期恶性肿瘤的一种有效方法。 Objective To investigate the curative effect of Aidi Injection on improving quality of life in patients with advanced malignant tumors. Methods 96 patients were divided into two groups by randomized double-blind method. The treatment group added Aidi Injection on the basis of chemotherapy and the control group received chemotherapy alone. The curative effect, Karnofsky score, T cell subsets, peripheral blood and liver and kidney function, clinical symptoms and other changes in patients who completed more than one course of treatment were measured and compared, and the two groups were compared. Results The effective rate was 44% in the treatment group and 43% in the control group in the short term. There was no significant difference between the two groups (56% in the control group and 56% in the control group) (P <0.05). Most immune function indexes (P <0.05). There were significant differences between the two groups in the improvement of clinical symptoms (except P <0.05 except for nausea and vomit, P <0.01). Conclusion Aidi injection combined with chemotherapy for the treatment of advanced malignancies has the effect of regulating immunity, reducing the side effects of chemotherapy and improving the quality of life of patients, and is an effective method for the treatment of advanced malignant tumors.