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镰刀菌毒素是镰刀菌属真菌产生的多种次生代谢产物的总称,在自然界中分布极为广泛,是危险的食品污染物,对人畜健康危害十分严重。因此,关于镰刀菌毒素的研究已成为当前国际上最紧迫的课题之一。通过对受侵染的宿主细胞以及体外培养的动物细胞研究表明,镰刀菌毒素可影响植物细胞膜透性并破坏其组织超微结构,可诱导体外培养的动物细胞发生凋亡。笔者对镰刀菌产毒素的类型,镰刀菌毒素对植物细胞、动物细胞的毒害以及脱毒方法作一综述。并探讨了当前镰刀菌毒素研究过程中存在的问题和未来的研究方向。
Fusarium toxin is a general term for a variety of secondary metabolites produced by Fusarium fungi. It is widely distributed in nature and is a dangerous food pollutant, which is very harmful to human and livestock health. Therefore, the research on Fusarium toxins has become one of the most pressing issues in the world. Studies on infected host cells and in vitro cultured animal cells show that Fusarium toxin can affect plant cell membrane permeability and destroy the ultrastructure of the tissue and induce apoptosis in cultured animal cells. The author of Fusarium toxin type, Fusarium toxin plant cells, animal cells and detoxification methods are reviewed. The problems existing in the research of Fusarium toxins and the future research directions are also discussed.