论文部分内容阅读
目的探讨血清同型半胱氨酸(HCY)及传统危险因素(胆固醇TC、甘油三酯TG)与冠心病间的关系。方法检测122例冠心病患者和100例健康人血清中HCY浓度及多项生化指标。结果冠心病组HCY和TG浓度明显高于对照组(P<0.05),但彼此间并不存在相关性(P>0.05);冠心病组高同型半胱氨酸血症(HHCY)的发病率明显高于对照组(P<0.05);不论是冠心病患者还是健康人群,HCY浓度都与年龄存在明显的相关性(P<0.05),与性别不相关。结论 HHCY可能是冠心病发生的一个独立危险因素;血清HCY的检测有助于冠心病的诊断;中老年人群应普查HCY浓度,以便更好的预防冠心病的发生。
Objective To investigate the relationship between serum homocysteine (HCY) and traditional risk factors (cholesterol TC, triglyceride TG) and coronary heart disease. Methods Serum concentrations of HCY and a number of biochemical parameters were measured in 122 patients with CHD and 100 healthy controls. Results The concentrations of HCY and TG in CHD group were significantly higher than those in control group (P <0.05), but there was no correlation between them (P> 0.05). The incidence of homocysteine (HHCY) (P <0.05). There was a significant correlation between HCY concentration and age (P <0.05) in both patients with coronary heart disease and healthy people, which was not related to gender. Conclusion HHCY may be an independent risk factor for CHD. The detection of serum HCY contributes to the diagnosis of coronary heart disease. HCY concentration should be surveyed in middle-aged and elderly patients in order to better prevent the occurrence of coronary heart disease.