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目的通过检测慢性肾衰竭患者CRP水平及EPO疗效的观察来探讨其相关的临床意义。方法选取糖尿病肾病导致慢性肾衰竭患者共30例:CRP正常组15例;CRP异常组15例。在EPO治疗前、后各采取静脉血标本检测CRP、血肌酐(SCr)、血红蛋白(Hb),并进行统计学t检验及χ2分析。结果CRP正常组及异常组治疗前Hb比较差异有统计学意义;CRP正常组治疗前、后Hb比较差异有统计学意义,而CRP异常组治疗前、后Hb比较差异无统计学意义。结论监测CRP水平在慢性肾衰竭患者慢性贫血的治疗中具有一定的临床参考价值。
Objective To investigate the clinical significance of detecting CRP level and the efficacy of EPO in patients with chronic renal failure. Methods A total of 30 patients with diabetic nephropathy who had chronic renal failure were enrolled: 15 in CRP normal group and 15 in CRP abnormal group. Before and after EPO treatment, venous blood samples were taken to detect CRP, serum creatinine (SCr), hemoglobin (Hb), and statistical t-test and χ2 analysis. Results There were significant differences in Hb between normal CRP group and abnormal group before and after treatment. The difference of Hb between normal CRP group before and after treatment was statistically significant, while there was no significant difference between before and after CRP abnormal group. Conclusion Monitoring CRP level has certain clinical value in the treatment of chronic anemia in patients with chronic renal failure.