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老年肺心病用呼吸机组与不用呼吸机组各30例尸检资料对照,结果:(1)用呼吸机组死于肺部感染占首位,χ2测验P<0.01。(2)用呼吸机组:肺泡间隔增宽,小气道狭窄、部分有透明膜和微血栓形成等改变,比不用呼吸机组病变严重P<0.05或0.01。(3)用呼吸机组中5例,超微结构检查发现肺泡亚型上皮细胞增生,透明膜与微血栓形成。(4)用呼吸机组其中2例x光片系统观察,肺片由清彻,逐渐出现双肺满布斑片状阴影。另就长期使用呼吸机出现的病理改变和机理进行了讨论。
Pulmonary heart disease in elderly patients with no breathing unit and 30 cases of autopsy data control, the results: (1) respiratory infection died of lung infection in the first place, χ2 test P <0.01. (2) with breathing unit: widened alveolar septa, small airway stenosis, some transparent membrane and micro-thrombosis and other changes than without respiratory disease serious P <0.05 or 0.01. (3) In 5 cases of respiratory group, ultrastructural examination revealed alveolar epithelial cell hyperplasia, hyaline membrane and microthrombosis. (4) 2 cases of respiratory system with x-ray system observation, the lungs by the clear, gradually covered with patchy lungs covered with shadow. Another long-term use of ventilator pathological changes and mechanisms were discussed.