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目的通过对1起1犬伤多人突发事件进行调查与处置,提高医务人员进行狂犬病暴露后预防处置(post-exposure prophylax?is, PEP)和应对突发事件的能力.方法 使用全国统一的《狂犬病病例个案调查表》对1起1犬伤多人突发事件的狂犬病暴露人群进行流行病学调查,及时进行PEP.通过实验室检测和随访观察狂犬病暴露后人群的PEP效果.结果 1犬伤41人,犬伤患者24 h内伤口规范处置率100%,疫苗接种率100%,被动免疫制剂使用率97.56%.犬伤患者全程狂犬病疫苗接种结束后20 d检测狂犬病病毒抗体均阳转,随访无狂犬病病例发生.结论 狂犬病暴露后规范的PEP可以有效防止狂犬病发生,降低严重犬伤事件的社会危害;应加强犬只管理,遏制严重犬伤事件发生.“,”Objective To improve the ability of medical staff to carry out post-exposure prophylaxis (PEP) and deal with emergencies through the investigation and treatment of the dog-biting event. Methods Epidemiological investigation was conducted on rabies exposed cases in an incident of dog-biting event by using “Rabies Case Questionnaire”. PEP was carried out in time. The effects of PEP were ob?served by laboratory test and follow-up. Results One dog injured 41 people. The standard wound disposal rate was 100%, vaccination rate of rabies vaccine was 100%, human immunoglobulin (HRIG) use rate was 97.56%. Antibodies against rabies virus of all cases were positive 20 days after the end of the vaccination. No cases of rabies occurred during the follow-up. Conclusion Standardized PEP after rabies expo?sure can effectively prevent the occurrence of rabies and reduce the social hazards of serious dog injury incident. Dog management should be strengthened to prevent the occurrence of dog injury incident.