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目的探讨铝碳酸镁联合奥美拉唑治疗胃溃疡合并胃出血的临床疗效。方法 82例胃溃疡合并胃出血患者,将其随机分成对照组和观察组,两组患者均经基础治疗,对照组41例患者单独使用奥美拉唑治疗,观察组41里联合铝碳酸镁、奥美拉唑治疗,评价比较两组的临床疗效。结果观察组治疗后症状评分为(4.8±0.8)分,对照组治疗后症状评分为(8.6±1.2)分,两组治疗后的症状评分均明显低于治疗前,观察组治疗后症状评分明显低于对照组,差异均具统计学意义(P<0.05);观察组总有效率为95.12%,对照组总有效率为75.61%,组间疗效比较差异具有统计学意义(P<0.05);观察组不良反应发生率为9.76%,对照组不良反应发生率为7.32%,组间比较差异无统计学意义(P>0.05)。结论铝碳酸镁联合奥美拉唑治疗胃溃疡合并胃出血的临床疗效显著,无严重不良反应,值得临床推广应用。
Objective To investigate the clinical efficacy of aluminum magnesium carbonate combined with omeprazole in the treatment of gastric ulcer combined with gastric hemorrhage. Methods Eighty-two gastric ulcer patients with gastric hemorrhage were randomly divided into control group and observation group. The two groups were treated by basic treatment. In the control group, 41 patients were treated with omeprazole alone. In the observation group, 41 cases were united with aluminum magnesium carbonate, Omeprazole treatment, evaluation and comparison of the clinical efficacy of the two groups. Results The symptom score of the observation group after treatment was (4.8 ± 0.8) points, and the symptom score of the control group was (8.6 ± 1.2) points after treatment. The symptom scores of the two groups after treatment were significantly lower than those before treatment, and the symptom scores of the observation group were obviously (P <0.05). The total effective rate was 95.12% in the observation group and 75.61% in the control group, the difference between the two groups was statistically significant (P <0.05). The incidence of adverse reactions in the observation group was 9.76%, and the incidence of adverse reactions in the control group was 7.32%. There was no significant difference between the two groups (P> 0.05). Conclusion The clinical curative effect of aluminum magnesium carbonate in combination with omeprazole in the treatment of gastric ulcer combined with gastric hemorrhage is significant, no serious adverse reactions, it is worth clinical promotion and application.