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作者用短小棒状杆菌(CP)免疫小鼠,以阐明中性粒细胞在巨噬细胞被激活过程中的作用。实验采用贴壁巨噬细胞毒试验和细胞化学分析等方法,证明吞食CP的中性粒细胞有激活巨噬细胞的作用。试验用6~8周龄AB6F1小鼠,腹腔免疫CP700μg/0.1ml后5小时,将分离出的2~5×10~6个炎症中性粒细胞腹腔注射到正常小鼠。4天后收集受
The authors immunized mice with Corynebacterium parvum (CP) to elucidate the role of neutrophils in the activation of macrophages. Experiments using adherent macrophage cytotoxicity test and cytochemical analysis and other methods to prove that swallowing CP neutrophils have the role of activating macrophages. The 6 ~ 8 weeks old AB6F1 mice were experimentally injected with 2 ~ 5 × 10 ~ 6 inflammatory neutrophils isolated from normal mice after intraperitoneal immunization of CP700μg / 0.1ml for 5 hours. Collect after 4 days