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1975年～1981年间,287名病人因患良性、非毒性甲状腺肿进行手术治疗,其中261例术后平均随访八年,进行单侧甲状腺叶切除199例,次全甲状腺切除62例。29例术后立即用甲状腺素(T_4)治疗以预防复发,其他病人出现甲减时才用甲状腺素治疗。本文旨在探讨良性、非毒性甲状腺肿术后常规服用甲状腺素是否必要,以及在次全甲状腺切除后发生甲减的可能性是否很高。有些研究表明:非毒性甲状腺肿术后预防性补充甲状腺素可以降低术后甲状腺肿复发。
Between 1975 and 1981, 287 patients underwent surgical treatment of benign and non-toxic goiter. Among them, 261 patients were followed up for an average of eight years. There were 199 unilateral thyroidectomy and 62 subtotal thyroidectomy. Twenty-nine patients were treated with thyroxine (T_4) immediately to prevent recurrence. Thyroxine was used in other patients when hypothyroidism occurred. This article aims to investigate whether benign and non-toxic thyrotoxicosis is routinely taken with thyroxine and whether hypothyroidism is likely to occur after subtotal thyroidectomy. Some studies have shown that prophylactic supplementation of thyroxine after non-toxic goiter can reduce postoperative goiter recurrence.