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目的分析百令胶囊联合低分子肝素治疗原发性肾病综合征的临床疗效。方法选取2009年5月至2011年5月我院收治的80例原发性肾病综合征患儿为研究对象,将其随机地分为治疗组和对照组。对照组40例患儿给予常规激素加低分子肝素治疗,治疗组40例患儿在常规激素和低分子肝素治疗的基础上联合百令胶囊治疗。对比两组患儿治疗前后24h Upro、Tc、Alb、BUN、Scr、PT以及Plt的变化。结果两组患儿治疗8周之后对比临床疗效。治疗组在治疗前后,24h Upro和Tc明显降低,Alb明显升高;与对照组相比,治疗组变化优于对照组。两组对比差异具有统计学意义(P<0.05)。结论在常规激素的基础上,使用百令胶囊联合低分子肝素治疗原发性肾病综合征能明显地改善患儿的临床症状,值得推广和应用。
Objective To analyze the clinical efficacy of Bailing capsule combined with low molecular weight heparin in the treatment of primary nephrotic syndrome. Methods Eighty children with primary nephrotic syndrome admitted to our hospital from May 2009 to May 2011 were selected as the study subjects and randomly divided into treatment group and control group. 40 children in the control group were treated with conventional hormone plus low molecular weight heparin, and 40 children in the treatment group were treated with Bailing capsule on the basis of conventional hormone and low molecular weight heparin. The changes of Upro, Tc, Alb, BUN, Scr, PT and Plt in two groups before and after treatment were compared. Results Two groups of children after 8 weeks of treatment compared the clinical efficacy. In the treatment group, the Upro and Tc were significantly decreased 24 hours before and after treatment, Alb significantly increased; compared with the control group, the treatment group than the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion On the basis of conventional hormones, the use of Bailing capsule combined with low molecular weight heparin in treating primary nephrotic syndrome can significantly improve the clinical symptoms of children, which deserves promotion and application.