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目的探讨厄贝沙坦治疗糖尿病肾病(DN)临床疗效。方法选取我院2008年6月至2011年5月144例糖尿病肾病患者,将其随机分成研究组和对照组,对照组使用常规治疗法,研究组在常规治疗基础上加用厄贝沙坦,比较分析两组患儿的治疗效果,治疗前后24h尿蛋变化情况。结果和对照组相比,研究组总有效率要明显高,差异有统计学意义(P<0.05)。经过12周治疗后,研究组和对照组的24h尿蛋白都有明显降低,研究组下降更明显,差异有统计学意义(P<0.05)。结论厄贝沙坦治疗糖尿病肾病明显明显,没有很显著的不良反应,可以改善糖尿病肾病患者肾脏功能。
Objective To investigate the clinical efficacy of irbesartan in the treatment of diabetic nephropathy (DN). Methods 144 patients with diabetic nephropathy from June 2008 to May 2011 in our hospital were randomly divided into study group and control group. The control group received conventional therapy. The study group was given irbesartan, Comparative analysis of the treatment effect of two groups of children, urinary egg changes 24 hours before and after treatment. Results Compared with the control group, the study group total effective rate was significantly higher, the difference was statistically significant (P <0.05). After 12 weeks of treatment, the 24-hour urinary protein in the study group and the control group were significantly decreased, the study group decreased more significantly, the difference was statistically significant (P <0.05). Conclusion Irbesartan treatment of diabetic nephropathy significantly, there is no significant adverse reactions, can improve renal function in patients with diabetic nephropathy.