论文部分内容阅读
目的:评价肾动脉支架置入术联合药物治疗肾移植术后粥样硬化性肾动脉狭窄(ARAS)患者的疗效。方法:选择肾移植合并ARAS患者93例,随机分为对照组与观察组。对照组行单纯药物治疗,观察组在单纯药物的基础上加用肾动脉支架置入术治疗,比较两组治疗前后血压、心功能指标变化及肾功能改善情况。结果:观察组治疗后收缩压(120.65±12.93)mmHg与舒张压(62.34±3.17)mmHg分别较对照组低(P>0.05);观察组治疗后LVEDD、心功能分级分别比对照组低,且LVEF(65.65±5.34)%比对照组高(P<0.05)。观察组肾功能获益率95.92%,明显高于对照组肾功能获益率72.73%(P<0.05)。结论:肾移植合并ARAS患者行肾动脉支架置入术与药物联合治疗,可有效调节患者血压,并改善其心功能及肾功能。
Objective: To evaluate the effect of renal artery stenting combined with drug treatment of atherosclerotic renal artery stenosis (ARAS) after renal transplantation. Methods: Ninety-three renal transplantation patients with ARAS were randomly divided into control group and observation group. The control group was treated with simple drug therapy. The observation group was treated with renal artery stenting on the basis of simple drugs. The changes of blood pressure, cardiac function and renal function were compared between the two groups before and after treatment. Results: After treatment, the systolic blood pressure (120.65 ± 12.93) mmHg and diastolic blood pressure (62.34 ± 3.17) mmHg in the observation group were lower than those in the control group (P> 0.05). LVEDD and cardiac function in the observation group were lower than those in the control group LVEF (65.65 ± 5.34)% higher than the control group (P <0.05). The benefit rate of renal function in the observation group was 95.92%, which was significantly higher than that in the control group (72.73%, P <0.05). Conclusion: Renal transplantation combined with ARAS can effectively regulate the blood pressure and improve its cardiac function and renal function in patients with ARAS.