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哺乳动物的天然免疫系统是通过CD14及TLR2 /TLR4两类受体识别入侵的细菌及其毒性成分。 1998年最先发现人类Toll样蛋白时 ,即发现TLR2可介导对细菌内毒素的反应 ,后来逐渐发现其识别谱广泛 ,还可识别革兰氏阳性菌、分支杆菌、酵母、肤聚糖、阿拉伯甘露糖脂、磷
The natural immune system of mammals is a type of bacteria that invades bacteria and their toxic components through both CD14 and TLR2 / TLR4 receptors. When human Toll-like protein was first discovered in 1998, TLR2 was found to mediate the bacterial endotoxin response and was subsequently found to have a broad spectrum of recognition and to recognize Gram-positive bacteria, mycobacteria, yeast, Arab mannose, phosphorus