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测定了37例流行性出血热患者血浆血栓素B_2(TXB_2)和6-酮-前列腺素F_(1α)水平,发现发热期和少尿期患者及有重度出血者血浆TXB_2/6-酮-PGF_(1α)(T/6)比值较正常对照明显降低,多尿、恢复期逐渐恢复正常。随病情加重,比值渐降低。上述改变有统计学意义。
Thromboxane B_2 (TXB_2) and 6-keto-prostaglandin F_1 (1α) levels were measured in 37 patients with epidemic hemorrhagic fever. The levels of plasma TXB_2 / 6-keto-PGF_ (1α) (T / 6) ratio was significantly lower than the normal control, polyuria, recovery gradually returned to normal. With the aggravation, the ratio gradually decreased. The above changes have statistical significance.