论文部分内容阅读
作者对21例开角型青光眼病人使用0.125%和0.25%的盐酸可乐宁(氯压定)滴眼剂与2%毛果芸香碱滴眼剂进行双盲交叉研究,以比较药物对眼内压和血压的作用。结果表明:上述两种浓度的可乐宁滴眼剂都可使眼内压下降,但作用强度不及毛果芸香碱,根据临床观察结果推算,0.4%的可乐宁与2%毛果芸香碱相当。可乐宁比毛果芸香碱优越之处为:降眼压的同时不缩小瞳孔。可乐宁滴眼剂可使病人收缩压及舒张压都有统计学意义的下降,但下降幅度不大。可乐宁滴眼剂作用持续时间超过4小时,且有着良好的
The authors conducted a double-blind crossover study of 21 patients with open-angle glaucoma using 0.125% and 0.25% clonidine hydrochloride (clonidine) eye drops and 2% pilocarpine eye drops to compare the effect of the drug on intraocular pressure and blood pressure effect. The results showed that the above two concentrations of clonidine eye drops can make the intraocular pressure decreased, but the intensity less than pilocarpine, based on clinical observations, 0.4% of the clonidine and 2% of pilocarpine equivalent. Clonidine is superior to pilocarpine as: Intraocular pressure without reducing the pupil. Colaoning eye drops can make patients with systolic and diastolic blood pressure decreased statistically, but the decline was not significant. Colaoning eye drops lasting more than 4 hours, and has a good