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目的:探讨重度宫腔粘连宫腔镜分离术后应用几丁糖配合球囊导尿管预防宫腔再粘连的疗效。方法:回顾性分析2005年1月～2010年1月在湖北医药学院附属人民医院宫腔镜确诊的68例重度宫腔粘连患者行宫腔镜下粘连分离术患者的相关临床资料,根据术后预防再粘连方法的不同,分为A组(球囊导尿管配合几丁糖组)和B组(球囊导尿管组),比较两组术后疗效及术后1、3、6个月随访宫腔再次粘连情况。结果:两组疗效比较,A组的治愈率及有效率明显高于B组,术后随访宫腔镜下宫腔形态,A组发生再粘连的几率显著低于B组,差异有统计学意义(P<0.05)。结论:重度宫腔粘连分离术后持续放置球囊导尿管并加用几丁糖预防术后再次发生宫腔粘连效果更佳,优于单纯使用球囊组,是安全、有效的方法,值得临床推广。
Objective: To investigate the curative effect of chitosan and balloon catheter in prevention of intrauterine reunion after severe intrauterine adhesions hysteroscopy. Methods: The clinical data of 68 patients with severe intrauterine adhesions diagnosed by hysteroscopy in Hubei Provincial People’s Hospital from January 2005 to January 2010 were retrospectively analyzed. According to the results of postoperative prevention Re-adhesion method is divided into group A (balloon catheter with chitosan group) and group B (balloon catheter group), the curative effect of two groups and postoperative 1, 3, 6 months Followed uterine adhesions again. Results: The cure rate and effective rate of group A were significantly higher than that of group B. The hysteroscopic morphology of uterine cavity was followed up in group A, the rate of re-adhesion in group A was significantly lower than that in group B, the difference was statistically significant (P <0.05). CONCLUSIONS: Continuous placement of balloon catheters with chitosan after severe intrauterine adhesions is better than intracavity alone in the treatment of postoperative intrauterine adhesions, which is safe and effective Clinical promotion.