Tectonic dynamic system transition, one of the main factors in metallogenesis, controls metallogenic fluid movement and ore body location in orefields and on an ore deposit scale (mainly in the continental tectonic setting), and even the formation and distribution of large-scale deposit clusters. Tectonic dynamic system transition can be classified as the spacious difference of the tectonic dynamic system in various geological units and the temporal alteration of different tectonic dynamic systems. The former results in outburst of mineralization, while the latter leads to the metallogenic diversity. Both of them are the main contents of metallogenic effect of tectonic dynamic system transition, that is, the alteration of dynamic system, the occurrence of mineralization, and the difference of regional tectonic dynamic system and metallogenic diversity. Generally speaking, the coupling of spatial difference of tectonic dynamic system and its successive alternation controlled the tempo-spatial evolution regularity of mineralization on a larger scale. In addition, the analysis of mineralization factors and processes of typical ore deposits proved that the changes of tectonic stress field, the direct appearance of tectonic dynamic system transition, may lead to the accident of mineralization physical-chemical field and the corresponding accidental interfaces were always located at ore bodies.