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目的观察酒石酸美托洛尔治疗老年慢性心力衰竭(CHF)的疗效和安全性。方法将72例CHF病人随机分为酒石酸美托洛尔组和对照组两组。观察酒石酸美托洛尔对患者心功能及心率(HR)的影响。结果酒石酸美托洛尔组总有效率高于对照组,其差异有显著性(P<0.01);酒石酸美托洛尔组心率较对照组显著减慢(P<0.05)。酒石酸美托洛尔组心功能较对照组显著改善(P<0.01)。结论在常规抗心衰治疗的基础上,加用酒石酸美托洛尔能显著改善老年慢性心力衰竭患者的心功能,提高患者的生活质量。
Objective To observe the efficacy and safety of metoprolol tartrate in the treatment of senile chronic heart failure (CHF). Methods Seventy-two CHF patients were randomly divided into metoprolol tartrate group and control group. To observe the effect of metoprolol tartrate on cardiac function and heart rate (HR) in patients. Results The total effective rate of metoprolol tartrate group was higher than that of control group (P <0.01). The heart rate of metoprolol tartrate group was significantly lower than that of control group (P <0.05). The cardiac function in metoprolol tartrate group was significantly better than that in control group (P <0.01). Conclusion On the basis of routine anti-heart failure treatment, adding metoprolol tartrate can significantly improve the cardiac function and improve the quality of life of elderly patients with chronic heart failure.