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1 实验材料 药物与试剂:被检药物熊胆注射剂由延边大学药学院药物分析教研室赵风泽教授配制和提供。阴性对照药物用等容量生理盐水(NS),为延边大学医学院附属医院药局自制品。阳性对照药物为血塞通注射液,昆明制药厂产品,批号951031。动物:家兔,体重2.2±0.2kg,雌雄兼用。昆明种小鼠,体重20±2g,雌雄各半。由延边大学医学院实验动物科提供。仪器:XSN-RⅡ型体外血栓形成血小板粘附两用仪,北京中医研究院西苑医院监制,无锡电子仪器二厂制造。
1 Experimental materials Drugs and reagents: The test drug bear gallbladder injection was prepared and provided by Professor Zhao Fengze of the Department of Pharmaceutical Analysis of the School of Pharmacy, Yanbian University. For the negative control drug, the same volume of physiological saline (NS) was used for the self-preparation of the Drug Administration of the Affiliated Hospital of Yanbian University Medical College. The positive control drug was Xuesaitong injection, Kunming Pharmaceutical Factory product, batch number 951031. Animals: Rabbits weighing 2.2 ± 0.2 kg, both male and female. Kunming mice, weighing 20 ± 2g, male and female. Provided by the Laboratory Animal Department of Yanbian University School of Medicine. Instruments: XSN-RII in vitro thrombosis platelet adhesion dual-purpose instrument, Beijing Institute of Traditional Chinese Medicine Xiyuan Hospital, Wuxi Electronic Instrument Factory.