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代谢综合征(MS)是多种代谢危险因素在同一个体内集结的病理状态。其病因和发病机制尚未完全阐明。近年来的研究认为MS是复杂的遗传因素及环境因素相互作用的结果。其中,腹型肥胖、慢性炎症及胰岛素抵抗及其相互作用在MS的发病机制中起了重要作用。尤其是炎症病因学理论备受关注,而肥胖、炎症与胰岛素抵抗之间的关系成为研究热点。
Metabolic syndrome (MS) is a pathological condition in which many metabolic risk factors aggregate in the same individual. The etiology and pathogenesis have not been fully elucidated. Recent studies suggest that MS is a complex genetic and environmental factors as a result of the interaction. Among them, abdominal obesity, chronic inflammation and insulin resistance and their interactions play an important role in the pathogenesis of MS. In particular, the theory of inflammatory etiology has drawn much attention, and the relationship between obesity, inflammation and insulin resistance has become a research hotspot.