目的：探讨精神病人感染莱姆病螺旋体情况。方法：间接免疫荧光抗体试验（ＩＦＡ）。结果：精神病人血清抗体阳性率（５２／１３４，３８９％）明显高于健康人群（１／９０，１１％），且均排除梅毒和钩端螺旋体感染，并从精神病人中分离出１株病原体。结论：莱姆病感染后期可致精神异常 Objective: To investigate the situation of spirochetes infected with Lyme disease in psychiatric patients. Methods: Indirect immunofluorescence antibody test (IFA). Results: The positive rate of serum antibody (52/134, 389%) in psychiatric patients was significantly higher than that in healthy people (1 / 90,11%), and both syphilis and leptospirosis were excluded and separated from mental patients A strain of pathogens. Conclusion: Lyme disease may lead to mental abnormalities late