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目的探讨青年肾细胞癌(肾癌)患者的临床特点、病理类型、诊治方法和预后。方法回顾性分析2004-2011年收治的64例年龄≤40岁的青年肾癌患者的临床资料,总结临床特点和诊治情况。结果男女比为2∶1。所有患者均接受手术治疗,根治性手术46例,保留肾单位术18例。术后临床分期Ⅰ期42例,Ⅱ期12例,Ⅲ期8例,Ⅳ期2例。病理分型分为肾透明细胞癌组47例(73.4%),非透明细胞癌组17例(26.6%)。2组患者的年龄、肿瘤大小、手术方式、临床分期等,差异均有统计学意义(P<0.05)结论青年肾癌早期症状隐匿,易被忽视。病理类型复杂,透明细胞癌组相对预后较好。早期诊断和治疗可改善预后。
Objective To investigate the clinical features, pathological types, diagnosis and treatment methods and prognosis of young patients with renal cell carcinoma (renal cell carcinoma). Methods The clinical data of 64 patients with renal cell carcinoma younger than 40 years who were admitted from 2004 to 2011 were analyzed retrospectively. The clinical features and diagnosis and treatment were summarized. Results male to female ratio of 2: 1. All patients underwent surgery, radical surgery in 46 cases, retained nephron in 18 cases. There were 42 cases in stage Ⅰ, 12 in stage Ⅱ, 8 in stage Ⅲ and 2 in stage Ⅳ. Pathological classification was divided into renal clear cell carcinoma in 47 cases (73.4%), non-clear cell carcinoma in 17 cases (26.6%). There were significant differences in the age, tumor size, operation method and clinical stage between the two groups (P <0.05) .Conclusion The early symptoms of renal cell carcinoma in young are hidden and easily overlooked. Pathological types of complex, clear cell carcinoma relative prognosis is good. Early diagnosis and treatment can improve the prognosis.