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目的建立99Tcm硫胶体(SC)显像法,测定小肠通过时间(SBTT),并与加服乳果糖法比较其通过时间及应用价值。方法用99TcmSC固体试餐对20例健康志愿者及26例胃肠道疾患患者进行显像,以测定SBTT;1周后,同一受试者进食核素加乳果糖试餐后以同样方法再次显像,并进行乳果糖氢呼气试验,或用反卷积分析法计算SBTT“谱”;或用50%结肠填充时间减50%胃排空时间计算平均SBTT。结果①20例健康志愿者的平均SBTT为(42±05)h;口盲肠时间为(43±06)h;乳果糖可加快SBTT,平均加快(18±06)h。②26例胃肠道疾患患者,由于疾病不同,SBTT改变不一。结论99TcmSC显像方法简单,无创,合乎生理。乳果糖可加快SBTT,缩短检查时间,有助于判断食物到达回盲部时间,有一定的应用价值。
Objective To establish a 99Tcm-sulfur colloid (SC) imaging method to determine the transit time of small intestine (SBTT), and compared with the lactulose plus lactation time and its application value. Methods Totally 20 healthy volunteers and 26 patients with gastrointestinal disorders were studied by 99TcmSC solid test to determine SBTT. After 1 week, the same subjects fed with radionuclide and lactulose test in the same way The images were re-visualized and the lactulose hydrogen breath test was performed, or the “SBTT” spectrum was calculated using deconvolution analysis; or the average SBTT was calculated using a 50% colon filling time minus 50% gastric emptying time. Results ① The average SBTT of 20 healthy volunteers was (42 ± 05) h. The duration of oral caecum was (43 ± 06) h. Lactulose accelerated SBTT and accelerated on average (18 ± 0 6) h. ② 26 cases of gastrointestinal disorders in patients with different diseases, SBTT changes. Conclusion 99Tcm SC imaging method is simple, non-invasive, in line with physiology. Milk fructose SBTT can speed up, shorten the examination time, help determine the time of arrival of food back blind, a certain value.