目的　总结分析韦格内肉芽肿临床特点 ,提高对该病的认识。方法　收集确诊的韦格内肉芽肿病例 ,对其临床表现、实验室检查、影像学特点以及治疗进行分析。结果　 18例患者中男 11例 ,女 7例 ,平均年龄 34岁 ,侵犯的组织器官包括 :肺、鼻咽、肾脏、眼、腮腺、关节及皮肤、前列腺等 ;抗中性粒细胞胞浆抗体 (ANCA)具有一定的诊断价值 ;“三多”是韦格内肉芽肿胸部影像学检查的特点。结论　韦格内肉芽肿可侵犯多个组织器官 ,临床症状缺乏特异性 ,提高对本病的认识是早期诊断的关键 ,早期治疗可获得较好的疗效 Objective To summarize and analyze the clinical features of Wegener’s granulomatosis and to improve its understanding of the disease. Methods We collected confirmed cases of Wegener’s granulomatosis and analyzed their clinical manifestations, laboratory tests, imaging features and treatment. Results Among the 18 patients, there were 11 males and 7 females, with an average age of 34 years. The infiltrating tissues and organs included lung, nasopharynx, kidney, eye, parotid gland, joint and skin, prostate and so on; anti-neutrophil cytoplasmic antibody (ANCA) has a certain diagnostic value; “more than three” is Wegener’s granuloma thoracic imaging features. Conclusion Wegener’s granulomatosis can invade multiple tissues and organs, and the clinical symptoms are not specific. To improve the understanding of this disease is the key point of early diagnosis, and early treatment can achieve better curative effect