测定17例良性乳腺组织和19例癌变乳腺组织Fourier变换红外光谱(FTIR),归属它们的吸收谱带,分析这2类乳腺组织的谱学的差异性,并探讨了乳腺组织细胞癌变的化学基础.结果表明这2类组织的FTIR谱图存在着显著的差异性.癌变乳腺组织细胞中,核酸的相对含量明显增加;胶原含量降低;蛋白质被磷酸化,分子间氢键受到破坏,蛋白质变得松散和无序. Seventeen cases of benign breast tissue and 19 cases of breast cancer tissue were measured by Fourier transform infrared spectroscopy (FTIR) and assigned to their absorption bands. The spectrum differences of these two types of breast tissue were analyzed, and the chemical basis of canceration of breast tissue was explored. The results show that there are significant differences in the FTIR spectra of these two types of tissues. The relative content of nucleic acids in cancerous breast tissue cells increases significantly; collagen content decreases; protein is phosphorylated, intermolecular hydrogen bonds are destroyed, and proteins become Loose and disorderly.