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It is vital to build an ideal animal model in studying diseases.This is also true of the case of hepatitis B.It is not only for the study of the infection or pathogenic mechanism of hepatitis B,but for the screening of anti-HBV agents.Transgenic mouse has been featured as the most idealistic model organisms.This literature review focuses on the methods of establishing transgenic mice model of hepatitis B virus in human and compares their characteristics.
It is vital to build an ideal animal model in studying diseases. This is also true of the case of hepatitis B. It is not only for the study of the infection or pathogenic mechanism of hepatitis B, but for the screening of anti-HBV agents .Transgenic mouse has been featured as the most idealistic model organisms. This literature review focuses on the methods of establishing transgenic mice model of hepatitis B virus in human and comparable their characteristics.