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目的了解我院药品不良反应发生特点及一般规律,促进临床合理用药。方法采用回顾性研究方法,对我院2011年收集的81例不良反应报告从患者性别、年龄、给药途径、药品种类、累及器官或系统及临床表现等方面进行统计、分析。结果 81例ADR中,抗感染药占45.7%,中药制剂占14.8%。静脉给药引发的ADR例数最多,以皮肤及其附件损害最多。结论临床应合理使用抗感染药及中药制剂,加强对中药注射剂的质量检测和规范使用,减少或避免ADR重复发生。
Objective To understand the characteristics and general laws of adverse drug reactions in our hospital and to promote rational drug use in clinic. Methods A retrospective study was conducted to analyze 81 cases of adverse reactions collected in our hospital in 2011 according to gender, age, route of administration, type of drugs, organ or systemic and clinical manifestations involved. Results 81 cases of ADR, anti-infectives accounted for 45.7%, Chinese medicine preparations accounted for 14.8%. The highest number of ADRs caused by intravenous administration, most damage to the skin and its annexes. Conclusion Clinical should be reasonable use of anti-infectives and traditional Chinese medicine preparations, to strengthen the quality of Chinese medicine injections and regulate the use of to reduce or avoid the recurrence of ADR.