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目的观察阿德福韦酯联合艾灸肝俞和期门穴抗病毒的临床效果。方法将80例抗病毒的乙型肝炎患者随机分为治疗组(n=40)及对照组(n=40),治疗组在保肝、阿德福韦酯抗病毒基础上加用艾灸肝俞、期门穴治疗,对照组用保肝和阿德福韦酯抗病毒治疗,全部病例连续治疗48周。结果 12周时治疗组患者食欲不振、乏力、肝肿大等临床症状与对照组比较有明显好转;治疗48周时HBV-DNA及HBeAg阴转情况较对照组有明显的提高(P<0.05)。结论阿德福韦酯联合艾灸肝俞、期门穴治疗能明显改善慢性乙型肝炎患者的症状,较单独应用阿德福韦酯能获得更好的抗病毒疗效。
Objective To observe the clinical efficacy of adefovir dipivoxil in combination with moxibustion, liver Yu and period gate antiviral. Methods Eighty patients with antiviral hepatitis B were randomly divided into treatment group (n = 40) and control group (n = 40). The treatment group was treated with moxibustion and liver protection plus adefovir dipivoxil Yu, period of treatment, the control group with liver protection and adefovir dipivoxil antiviral therapy, all cases of continuous treatment for 48 weeks. Results After 12 weeks of treatment, the clinical symptoms such as loss of appetite, fatigue and hepatomegaly in the treatment group were significantly improved compared with those in the control group. The levels of HBV DNA and HBeAg were significantly increased at 48 weeks (P <0.05) . Conclusion Adefovir dipivoxil combined with moxibustion and liver Yu and period of portal therapy can significantly improve the symptoms of patients with chronic hepatitis B, adefovir dipivoxil alone can get better antiviral efficacy.