患者男 ,2 7岁 ,其妻怀孕 3次 ,第 1、2、3胎孕 6 0多天 ,均不明原因发生自然流产 ,孕期均无患病 ,无射线及有害物质接触 ,也无外伤 ,夫妻表型及智力正常 ,非近亲婚配 ,否认母亲有流产史。细胞遗传学检查 :取外周血淋巴细胞培养 ,制片 ,染色体G显带 ,分析 30个中期分裂相 ,患者 Male patient, 27 years old, his wife was pregnant 3 times, 1, 2, 3 gestational pregnancy more than 60 days, are unexplained spontaneous abortion, no disease during pregnancy, no radiation and harmful substances in contact, nor trauma, The couple’s phenotype and intelligence normal, non-relatives marriage, denied the mother had a history of abortion. Cytogenetic examination: Peripheral blood lymphocyte culture, preparation, chromosome G banding, analysis of 30 metaphase, patients