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作者报告了江苏省在风疹疫苗使用前人群的自然免疫状况,4岁以下年龄组血凝抑制(HI)抗体阳性率在25%以下,随着年龄的增长,自然免疫水平增高,13~25岁人群阳性率约在80%左右。接种风疹疫苗1月后,抗体100%阳转,GMT从免前的13.33上升至243.16,说明国产BRDⅡ株风疹减毒活疫苗具有良好的免疫原性。对于免前阳性人群,风疹疫苗接种后抗体亦有显著性上升
The authors report on the natural immune status of the population before use of rubella vaccine in Jiangsu Province. The positive rate of HI antibody in children under 4 years of age is below 25%. As the age increases, the level of natural immunity increases, reaching 13-25 years The positive rate of about 80% of the population. After 1 month of immunization with rubella vaccine, the antibody was 100% positive and the GMT increased from 13.33 to 243.16, indicating that the live attenuated BRD II vaccine had good immunogenicity. For the pre-immune positive population, antibodies to rubella vaccines also increased significantly