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ＤｅＦｌｏｒａ等［１］和刘淑英等［２］均证实Ｎ乙酰半胱氨酸（ＮＡＣ）具有抗诱变性，ＤｅＦｌｏｒａ等［３］和Ｋａｄａ等［４］报道了ＮＡＣ对诱变剂导致的ＤＮＡ损伤的修复作用。我们以Ｌ半胱氨酸为参比，观察了ＮＡＣ对乌拉坦诱发的小鼠骨髓细胞姐妹染色单体交换率?
DeFlora et al [1] and Liu Shuying et al [2] confirmed N-acetylcysteine (NAC) has mutagenicity, DeFlora et al [3] and Kada et al [4] reported that DNA induced by mutagen NAC Damage repair effect. We L-cysteine as a reference to observe the NAC urethane-induced mouse bone marrow cells sister chromatid exchange rate?