新生儿硬肿症是由寒冷和感染等因素引起微循环障碍而导致以皮下脂肪硬化和皮下水肿为特征的一种疾病。它多发生于寒冷季节,特别是未成熟儿及感染儿发病率较高。临床特点为体温低、皮肤冷,皮下脂肪所积聚的部位出现水肿、发硬。其病死率高达 55.8％。为了降低病死率,我们于1981年1月至1985年3月应用东莨菪碱治疗新生儿硬肿症25例,取得了较好疗效,现小结于下。一、诊断标准新生儿硬肿症的诊断标准见表1。 Neonatal scleredema is a disorder characterized by subcutaneous fat sclerosis and subcutaneous edema caused by microcirculation disorders such as cold and infection. It occurs mostly in the cold season, especially in infants and children with a higher prevalence. Clinical features of low body temperature, cold skin, subcutaneous fat accumulation site edema, hair stiff. The case fatality rate as high as 55.8%. In order to reduce mortality, we in January 1981 to March 1985 scopolamine treatment of 25 cases of neonatal sclera, and achieved good results, now summarized in the following. First, the diagnostic criteria for the diagnosis of neonatal sclerosis in Table 1.