论文部分内容阅读
[目的]探讨腹腔镜辅助阴式手术对早期老年子宫内膜癌患者术后血清IGF-1、CA125水平及生存质量的影响.[方法]选择早期老年子宫内膜癌患者104例,根据患者意愿分为观察组和对照组,每组52例.对照组采用传统开腹手术治疗,观察组采用腹腔镜辅助阴式手术治疗.比较两组患者手术时间、术中出血量、术中淋巴结清扫个数、肛门排气时间、住院时间及术后并发症发生率和手术前、术后1个月血浆人胰岛素样生长因子-1(IGF-1)和癌抗原125(CA125)水平和术后SF-36生活质量评分,统计两组患者1年内复发转移率及1年生存率并比较.[结果]观察组术中出血量、肛门排气时间、住院时间、术后并发症发生率均较对照组减少(P00.5);两组术前、术后1个月CA125、IGF-1水平比较差异均无统计学意义(P>00.5);两组患者1年生存率、复发率比较差异均无统计学意义(P>00.5);观察组术后SF-36生活质量量表生理总得分和心理总得分均显著高于对照组(P00.5) .There was no significant difference in the 1 year survival rate and recurrence rate between the two groups ( P >00.5);The SF-36 quality of life scale ,total physiological score and psycho-logical scores of the observation group were significantly higher than those of the control group ( P <00.5) .[Conclusion]The laparoscopic assisted vaginal surgery for early stage endometrial carcinoma in the elderly can achieve the same extent as open surgery in range of operation ,effect of resection and postoperative survival rate ,and can reduce surgical trauma and the incidence of postoperative complications ,improve the quality of life ,which is worthy of clinical application .