４３例原发性胃肠道非霍奇金淋巴瘤，临床表现均无特异性，术前误诊率高，主要接受单纯手术或手术＋化疗。随访中发现，手术＋化疗组３年、５年生存率分别为７３．９％和６５．２％，而单纯手术组则分别为３８．９％和２７．８％，两组差异有显著性（Ｐ＜０．０５）。笔者认为对本瘤应采取以手术为主的综合治疗，并认为术后正规、系统地化疗将会对本病的治疗发挥更大的作用 43 cases of primary gastrointestinal non-Hodgkin’s lymphoma, no specific clinical manifestations, preoperative misdiagnosis rate, mainly to accept surgery or surgery + chemotherapy. During follow-up, the three-year and five-year survival rates of the surgery+chemotherapy group were 73.9% and 65.2%, respectively, compared with 38.9% and 27.8%, respectively, in the surgery alone group. There was a significant difference between the two groups. (P<0.05). The author believes that the surgery should be based on a comprehensive treatment of the tumor, and that regular, systematic chemotherapy will play a greater role in the treatment of this disease